Which of the following is a risk factor for asthma-related death?

The use of more than one metered-dose inhaler of a short-acting β-agonist per month is a significant risk factor for asthma-related death. This indicates that a patient is likely experiencing more frequent and severe asthma symptoms, leading to the need for increased use of rescue medication. Short-acting β-agonists are intended for quick relief of acute asthma symptoms, and reliance on them can suggest that the underlying asthma is not well-controlled.

This frequent use can be a warning sign that the asthma management plan is inadequate, which can increase the risk of severe exacerbations. If asthma is not properly managed, it may lead to life-threatening conditions. Therefore, understanding this relationship is vital for assessing the severity of the asthma condition and implementing necessary interventions to improve control and reduce the risk of serious outcomes.

In contrast, using one metered-dose inhaler monthly may indicate better control over asthma, and infrequent exposure to allergens generally reduces the likelihood of asthma exacerbations. Regular physical exercise, when performed with proper management, can often improve lung function and overall health in individuals with asthma.