Which asthma agent is preferred for a pregnant female with mild persistent asthma?

Inhaled corticosteroids are the preferred treatment for a pregnant female with mild persistent asthma due to their effectiveness and safety profile. During pregnancy, maintaining asthma control is crucial for both the mother and the developing fetus. Inhaled corticosteroids provide targeted delivery of medication to the airways, helping to reduce inflammation and improve airway function with minimal systemic absorption. This localized action decreases the risk of potential side effects that systemic medications might pose to the fetus.

Inhaled corticosteroids are generally considered safe throughout pregnancy, as extensive studies have shown that they do not increase the risk of adverse pregnancy outcomes. They are effective in managing asthma symptoms and preventing exacerbations, making them suitable for ongoing management in pregnant patients.

In contrast, other options may not be appropriate for pregnant individuals. Oral corticosteroids could pose risks to the fetus when used systemically and are typically reserved for more severe cases. Leukotriene receptor antagonists and long-acting β-agonists have more limited evidence regarding their safety during pregnancy, making them less favorable choices in this scenario.